Dizygotic twinning
نویسندگان
چکیده
منابع مشابه
Dizygotic twinning.
The tendency to conceive spontaneous dizygotic (DZ) twins is a complex trait with important contributions from both environmental factors and genetic disposition. Twins are relatively common and occur on average 13 times per 1000 maternities, though the twinning frequency varies over time and geographic location. This variation is mostly attributed to the differences in DZ twinning rate, since ...
متن کاملBody composition, smoking, and spontaneous dizygotic twinning.
OBJECTIVE To examine differences in body composition and smoking between mothers of spontaneous monozygotic and dizygotic twins, while taking into account maternal age, gravidity, and educational attainment. DESIGN Retrospective cohort study. SETTING The Netherlands Twin Register. PATIENT(S) Mothers of twins (n = 19,357) registered with the Netherlands Twin Register. Data were selected fr...
متن کاملGenetics of dizygotic twinning: a feasibility study for a biobank.
To locate the genes that make a substantial contribution to variation in natural dizygotic twinning in humans, large-scale studies are needed. New studies should not stop at DNA genotyping, but collect material that allow gene-expression analysis, transcriptomics, proteomics and endocrinology. In this article we describe a pilot study to examine the feasibility, effectiveness and logistics of l...
متن کاملA genome wide linkage scan for dizygotic twinning in 525 families of mothers of dizygotic twins.
BACKGROUND The tendency to conceive dizygotic (DZ) twins is a complex trait influenced by genetic and environmental factors. To search for new candidate loci for twinning, we conducted a genome-wide linkage scan in 525 families using microsatellite and single nucleotide polymorphism marker panels. METHODS AND RESULTS Non-parametric linkage analyses, including 523 families containing a total o...
متن کاملGenetic modelling of dizygotic twinning in pedigrees of spontaneous dizygotic twins.
The inheritance of spontaneous dizygotic (DZ) twinning was investigated in 1,422 three-generation pedigrees ascertained through mothers of spontaneous DZ proband twins. DZ twinning was modelled as a trait expressed only in women. The penetrance was modelled first as a parity independent and secondly as parity dependent. The observed frequencies of maternal and paternal grandmothers with DZ twin...
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ژورنال
عنوان ژورنال: Human Reproduction Update
سال: 2007
ISSN: 1460-2369,1355-4786
DOI: 10.1093/humupd/dmm036